Chemotherapy of Cutaneous Herpesvirus Infection of Hairless Mice
نویسندگان
چکیده
منابع مشابه
Cutaneous transcriptome analysis in NIH hairless mice
Mice with spontaneous coat mutations are ideal animal models for studying skin development and tumorigenesis. In this study, skin hair growth cycle abnormalities were examined in NIH hairless mice 42 days after birth (P42) by using hematoxylin-eosin (H&E) staining. To examine the gene expression patterns in the skin of mutant mice, the dorsal skin of P42 female NIH mice and NIH hairless mice wa...
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Passively immunized hairless mice were inoculated cutaneously with herpes simplex virus. Thirty-nine days later, when the primary cutaneous lesions had completely healed, the mice were treated subcutaneously with prednisone. Within 12 to 30 days after starting prednisone treatment, herpesvirus was recovered by skin swabs from 12 of 71 (17%) of the treated mice. This new model has potential appl...
متن کاملHairless Mice
After Melish and Glasgow reported that an experimental infection resembling the scalded-skin syndrome in humans could be produced by certain strains of Staphylococcus aureus in neonatal mice (3) and after the subsequent demonstration that this response was mediated by a soluble protein called exfoliatin (2), it was recognized that Swiss mice became refractory to this toxin about 5 days after bi...
متن کاملHuman herpesvirus 8 infection in patients with cutaneous lymphoproliferative diseases.
OBJECTIVE To investigate the prevalence of human herpesvirus 8 (HHV-8; Kaposi sarcoma-associated herpesvirus) infection in patients with lymphoproliferative skin diseases such as large-plaque parapsoriasis (LPP) and mycosis fungoides compared with inflammatory cutaneous conditions or healthy control subjects. DESIGN A survey study was undertaken in 123 subjects with various clinical condition...
متن کاملIn vivo standardization of cutaneous bactericidal activity of antiseptics by using monoxenic hairless mice.
This study was designed to investigate the bactericidal activities of antiseptics on the cutaneous flora of hairless mice monoxenic to Staphylococcus epidermidis, Staphylococcus aureus, or Pseudomonas aeruginosa in vivo. A standardized method for testing such antiseptics to compare their bactericidal effectiveness in humans in described. Seven antiseptics belonging to seven different chemical g...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1973
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12724476